Recent advances in molecular diagnostics and drug development have revolutionized how cancer is being diagnosed, risk stratified and treated. A host of new targeted therapies and immunotherapies have emerged, and many require companion diagnostic testing to identify which patients are most likely to respond to these therapies. This activity will cover recent advances in cancer diagnostics, with a focus on integrating precision medicine approaches. Topics will cover the latest molecular and genomic biomarkers used in cancer diagnostics, including their clinical implications for targeted therapies. Learners will gain insights into selecting and interpreting biomarker tests that drive individualized treatment decisions and improve patient outcomes.